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The crash happened just after 10:30 p.m. at 1292 North St. in Pittsfield when a southbound Chevrolet Silverado truck slammed into a northbound Nissan Rogue, Pittsfield police said.
The driver of the Rogue was rushed to Berkshire Medical Center with life-threatening injuries and later taken to Baystate Medical Center, authorities said. A passenger in the car and the driver of the pick-up were also taken to an area hospital with minor and serious injuries, respectively, officials said.
Authorities did not release their names.
Police shut down a section of North Street until 3 a.m. on Saturday as they cleared the area.
Pittsfield officers are investigating the crash.
Police ask witnesses of the crash or anyone with information to contact the Pittsfield traffic unit at 413-448-9700 ext. 596.
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